Jeju Hallabong (Citrus), the source material for Immune Polys.
Immune Polys is a bioconverted Jeju Hallabong polysaccharide standardized to rhamnogalacturonan (RG-II), studied for immune activation and anti-cancer effects in a 100-subject, 12-week human clinical trial.
Ingredient specification
- Brand nameImmune Polys®
- Ingredient nameCitrus Hallabong
- Manufacturing methodBioconversion
- Marker compoundRhamnogalacturonan (RG-II)
- Recommended intake100 mg per day, as Hallabong polysaccharide (RG-II)
- OriginJeju, Korea
What Immune Polys does
- Immune activation
- NK cell support
- Anti-cancer activity
- Inflammation balance
Immune Polys is produced by bioconversion of Citrus Hallabong grown on Jeju, concentrating the cell-wall polysaccharide rhamnogalacturonan (RG-II) that drives the ingredient's activity. The marker compound is used to standardize each batch.
Clinical results
The trial was conducted at the Ilsan Hospital Health Center with 100 adult men and women, who consumed Immune Polys for 12 weeks. Safety was confirmed over the full 12 weeks of consumption.
| Test | Before (pg/mL) | After (8 weeks) | Outcome | p |
|---|---|---|---|---|
| IL-12 | 42.4 ± 5.5 | 53.9 ± 5.6 | Immune boost | 0.027 |
| IFN-γ | 5.57 ± 2.1 | 9.48 ± 1.8 | Anti-cancer activity | 0.037 |
| IL-6 | 2.92 ± 0.3 | 2.43 ± 0.3 | Inflammation reduced | < 0.01 |
| IL-1β | 0.55 ± 0.0 | 0.51 ± 0.0 | Inflammation reduced | < 0.01 |
Note: results may vary by individual.
Patent & journal
- Patent
KR 10-1530982(Immunity) ·KR 10-1561648(Anti-cancer) - JournalCarbohydr Polym. 2014 Oct 13;111:72–9.
- JournalFood Funct. 2016 Jun 15;7(6):2833–9.
Source botanical. Immune Polys is derived from Citrus Hallabong cultivated and harvested on Jeju. The marker compound, rhamnogalacturonan (RG-II), is a cell-wall polysaccharide concentrated by bioconversion and used to standardize each batch.