Milk phospholipid powder, the ingredient class behind Milkogni

Milk phospholipid extract, standardized to sphingomyelin · the ingredient class behind Milkogni.

Milkogni is a milk-derived phospholipid ingredient that supplies the building blocks of the neuronal cell membrane. Standardized to sphingomyelin and supported by a 12-week human clinical trial, it is formulated to support memory, attention and cognitive function.

At a glance

Ingredient specification

  • Brand nameMilkogni®
  • Ingredient nameMilk Phospholipids
  • Manufacturing methodUltrafiltration followed by ethanol extraction
  • Marker compoundSphingomyelin, 1% or more
  • Recommended intake500 mg per day, as milk phospholipid extract
  • OriginKorea, Germany
Functions & features

What Milkogni does

  • Composition of the brain cell membrane
  • Activation of neurotransmitters
  • Improvement of memory and cognition

The marker compound is sphingomyelin. Recovered and concentrated by ultrafiltration followed by ethanol extraction, the process is designed to enrich the membrane-derived phospholipid fraction while keeping the marker compound intact, supporting brain cell membrane structure, neurotransmitter activity, and memory and cognitive function.

Human clinical trial

Clinical results

23%
Greater improvement in attention and concentration (Auditory CPT) versus placebo.
+3.81
Intra-group improvement in Auditory CPT attention score in the test group.

The trial was conducted at Yangsan Pusan National University Hospital, where 100 adult men and women consumed Milkogni for 12 weeks. The test group showed a significant 23% greater improvement in attention and concentration (Auditory CPT) relative to the placebo group. Milkogni was proven safe over the 12-week consumption period.

Efficacy results summary — clinical test
TestEndpoint (method)Absolute change (test group)Relative efficacy (vs. placebo)
AttentionAuditory CPT score+3.81 points23% higher improvement (p=0.045)
Global cognitionCNT total score+1.31 pointsPositive improvement trend
NeuroprotectionBDNF stabilizationLoss inhibitedImprovement trend
AntioxidantMDA inhibition-0.01 levelsLowering of oxidative stress

Note: results may vary by individual.

References

Patent & journal

  • PatentKR 10-2024-0062252 · PCT/KR2024/020955
  • JournalJ Am Oil Chem Soc. 2025;102(3):467–476.

Source. Milkogni is made from milk phospholipids supplied from Korea and Germany, standardized to at least 1% sphingomyelin as the marker compound.